Organ Preservation Market: Global Industry Analysis and Forecast (2024-2030) by Type, Technique and Application

  • Organ Preservation Market size was valued at US$ 260 Mn. in 2023 and the total Global Organ Preservation Market revenue is expected to grow at a CAGR of 6.6% from 2024 to 2030, reaching nearly USD 406 Mn. in 2030.

  • Format : PDF | Report ID : SMR_1634

Organ Preservation Market Overview

The term "organ preservation" describes the procedures and methods employed, usually during organ transplantation, to preserve the viability and functionality of organs outside the body. Ensuring the organs are in perfect condition before transplanting them to a recipient is an essential part of the organ transplantation process. The quality of donor organs has been improved by the development of numerous preservation methods and treatments, which have a direct effect on post-transplant morbidity and survival. The Organ Preservation consists of 2 key methods, which include Hypothermic Storage and Sub-zero Organ Preservation. Organ preservation is essential for prolonging the ischemia period of vital organs such as the liver, pancreas, and kidneys, which enables effective organ transplantation and better patient outcomes.

 

The Organ Preservation Market has seen a substantial increase with a projected CAGR of 6.6% for the projected year 2030. Several factors influence the Organ Preservation Market such as constant Technological advances, increasing organ transplantation procedures, Rising healthcare investment, and a growing geriatric population. The market is adversely affected by some major restraining factors which include the shortage of some organs, rejection of organs, high costs associated with organ transplantation and preservation, and limited access to care. The Organ Preservation Market is segmented By Type, Technique, and Application.

 

The Organ Preservation Market is segmented through regions in North America, Europe, Asia-Pacific, the Middle East and Africa, and South America. The North American region holds approximately 42.59% of the total market revenue being the most dominant region in the Organ Preservation market as of 2023.  This dominance is attributed to factors like an increase in the number of cases of end-stage renal disease (ESRD) and the consequent growth in kidney transplants, which ultimately fuels the demand for organ preservation solutions.  North American region is followed by Europe holding the second-largest share globally. Whereas, Asia-Pacific is projected to grow at the quickest CAGR in the projected period.

 

Some of the key players dominating the Organ Preservation Market are- 21st Century Medicine Inc., Dr. Franz Köhler Chemie GmbH, Essential Pharmaceuticals LLC, IGL GmbH, Lifeline Scientific Inc., Organ Recovery Systems Inc., Preservation Solutions Inc., XVIVO Perfusion AB, Bridge to Life Ltd., Paragonix Technologies Inc., TransMedics Inc., Waters Medical Systems LLC, BioLife Solutions Inc., Bristol-Myers Squibb Company, CryoLife Inc., Hemarina SA, BioTime Inc., Lifor SA, TissueGene Inc., ToleroTech Inc.

Organ Preservation Market

 

Organ Preservation Market Dynamics

Technological Advancements-

Technological advances play a key role in helping the Organic Preservation Market to grow due to the recent developments in technologies such as Perfusion Systems for solid organ preservation, improving the viability of organs like heart, liver, kidneys, and Vascularized composite allograft (VCA). Organ Preservation Technology is experiencing substantial growth in the US and Canadian markets with a projected increase of CAGR 6.6% for the forecasting period. Also with the introduction of technologies like normothermic, hypothermic machine perfusion, and static cold storage (SCS), the market has grown significantly.

 

Increasing Organ Transplantation Procedures- One of the main factors fuelling the organ preservation market is the rise in organ transplant operations. This is because the need for organ preservation solutions is being driven by an increase in end-stage renal disease (ESRD) cases and kidney transplants. End-stage renal Disease (ESRD) in the United States between 2001 and 2020 shows a significant rise in the prevalence of ESRD. The number of ESRD patients increased from 97,856 in 2001 to 134,837 in 2020 which is an increase of 37.8%.  The market for organ preservation was dominated by the organ transplant centers segment. The primary element boosting the acceptability of this end-user is the growing number of transplant centers worldwide.

Organ Preservation Market1

Rising Healthcare Investment- Significant research and development efforts in the field of organ preservation are facilitated by increased investments in healthcare. This funding encourages the investigation of novel methods that improve the efficacy of preservation measures. For Instance, the US Department of Agriculture funded 500 million USD through a new program in the year 2022 aiming to support innovative projects in organ preservation and biotechnology. The National Institutes of Health (NIH) invested 17.2 USD billion for research on all vaccine technologies before 2020. Upgrades to the infrastructure supporting healthcare, especially organ transplant centers, are being funded. By facilitating effective organ preservation procedures, this infrastructural development hopes to provide ideal circumstances for organ storage and transplantation. Investments have bolstered joint efforts between public and private institutions, creating a favorable atmosphere for organ preservation developments. These collaborations are essential for advancing research and development initiatives.

 

Organ Shortage- Due to the limited supply of organs available for transplantation, organ shortage is a major factor impeding the growth of the organ preservation industry. For instance, in the United States, as of January 2022, over 106,588 patients were waiting for organ transplants, however by the end of 2021, just 41,354 operations had been carried out. There is an increasing need for efficient organ preservation methods and solutions as a result of this disparity between the amount of organs donated and the amount of organs needed. Poor legislative measures, a higher danger of organ trafficking, and a lack of awareness about organ donation are the main causes of the low number of organs donated each year. To solve these problems, the governments of several nations are enacting new legislation; nevertheless, the process is sluggish, and the shortage continues.  

 

Organ Rejection- Organ rejection is a significant challenge that proves to be a key restraining factor for the Organ Preservation market. Organ rejection occurs when the recipient's immune system attacks the transplanted organ, leading to organ failure and the need for transplantation or other treatments. This issue contributes to the limited success rate of organ transplantation, which in turn affects the demand for effective organ preservation techniques and solutions. The goal of organ preservation procedures is to keep organs functional and viable outside of the body, which is essential for a successful transplant. Nonetheless, patients and healthcare professionals continue to have serious concerns about the possibility of organ rejection. Immune Response Challenges, Allograft Rejection, Chronic Rejection, Hyperacute rejection, and Secondary rejection are some of the major cases found in the Organ Rejection phenomena.

 

Organ Preservation Market Segmentation

By type, the Organ Preservation market is further divided into Kidney, Heart, Lung, Liver, and Pancreas. The Kidney segment holds the highest market share in 2023 with a projected CAGR of 7%. The kidney is followed by the Liver for the second highest market share in the Organ Preservation Market. Though the lungs and heart segment are a key contributor to the Organ Preservation Market their market shares are smaller than Kidneys and livers.

 

By Technique, is divided into Static Cold Storage, Hypothermic Machine Perfusion, and Normothermic Machine Perfusion. Static Cold storage is a conventional method that involves the cold storage of organs in a refrigerated, static environment. SCS is primarily used for the preservation of kidney, liver, and pancreas preservation.  Hypothermic Machine Perfusion (HMP) is a technique where perfusing the organ with a cold solution is done and the circulation is done through a machine. The technique provides dynamic preservation which reduces ischemic injury and improves organ efficiency. Whereas, Normothermic Machine Perfusion (NMP) is a technique that provides perfusion at near body temperature, which induces physiological conditions. It comes with certain advantages that mimic natural organ function, which decreases the ischemic damage and potentially increases the preservation time.

 

By Application, the segment is further divided into pharmaceuticals, Organ transplantation, Speciality Centres, and Hospitals. Pharmaceuticals use the preservation of organs for studying drugs, toxicity testing, and other pharma research. Whereas, in Organ Transplantation preservation helps the quality and viability of organs in the transplant process. Hospitals use organ transplants and other medical interventions that are required as they grow their medical capabilities which provides enhanced services and treatments.

Organ Preservation Market2

Competitive Landscape of Organ Preservation Market

The market for organ preservation is very competitive, with multiple major companies in the market. Which includes 21st Century Medicine Inc., Dr. Franz Köhler Chemie GmbH, Essential Pharmaceuticals LLC, IGL GmbH, Lifeline Scientific Inc., Organ Recovery Systems Inc., Preservation Solutions Inc., XVIVO Perfusion AB, Bridge to Life Ltd., Paragonix Technologies Inc., TransMedics Inc., Waters Medical Systems LLC, BioLife Solutions Inc., Bristol-Myers Squibb Company, CryoLife Inc., Hemarina SA, BioTime Inc., Lifor SA, TissueGene Inc., ToleroTech Inc. To increase their market share, these businesses are constantly collaborating, merging, and developing new technologies. For instance-

 

In 2020, Dr. Franz Köhler Chemie GmbH (Germany) entered into a joint venture with Melchers Group and CICEL (Germany) to establish Köhler in China for the distribution of Custodiol HTK solutions for cardiac and transplant surgery in the Chinese market.

 

OrganOx's Growth Investment: OrganOx, a medical device company, bagged a €29 million growth investment led by Lauxera Capital Partners to advance organ transplantation practices.

 

Paragonix Technologies: Organ preservation company Paragonix Technologies secured $24 million in Series B funding, led by Signet Healthcare Partners.

 

Bridge to Life Ltd- in August 2021, Bridge to Life announced the first close of a $56 million growth financing round led by Perceptive Advisors. The company is also being involved in strategic mergers such as In August 2021 it merged with Tevosol to commercialize a portable normothermic machine preservation technology platform for organ transplantation is one of the company's past mergers.

 

TissueGene Inc- TissueGene Inc., formerly known as Kolon TissueGene, is dedicated to creating gene and cell therapies for osteoarthritis conditions that impact joints such as the hips, spine, and knees. There isn't much information available right now regarding investments, however, on May 15, 2023, Kolon TissueGene closed a deal with a single investor providing 30 million Korean Won in cash.

Organ Preservation Market Scope

Market Size in 2023

USD 260 Mn

Market Size in 2030

USD 406 Mn

CAGR (2024-2030)

6.6%

Historic Data

2018-2022

Base Year

2023

Forecast Period

2024-2030

Segment Scope

By Type  

  • Kidney
  • Heart
  • Lung
  • Liver
  • Pancreas

By Technique

  • Static Cold Storage
  • Hypothermic Machine Perfusion
  • Normothermic Machine Perfusion

By Application

  • Pharmaceuticals
  • Organ Transplantation
  • Speciality Centres
  • Hospitals
  • Others

Regional Scope

North America- United States, Canada, and Mexico

Europe – UK, France, Germany, Italy, Spain, Sweden, Austria, and Rest of Europe

Asia Pacific – China, India, Japan, South Korea, Australia, ASEAN, Rest of APAC

Middle East and Africa - South Africa, GCC, Egypt, Nigeria, Rest of the Middle East and Africa

South America – Brazil, Argentina, Rest of South America

 

Organ Preservation Market Key Players

  • 21st Century Medicine Inc.
  • Dr. Franz Köhler Chemie GmbH
  • Essential Pharmaceuticals LLC
  • IGL GmbH
  • Lifeline Scientific Inc.
  • Organ Recovery Systems Inc.
  • Preservation Solutions Inc.
  • XVIVO Perfusion AB
  • Bridge to Life Ltd.
  • Paragonix Technologies Inc.
  • TransMedics Inc.
  • Waters Medical Systems LLC
  • BioLife Solutions Inc.
  • Bristol-Myers Squibb Company
  • CryoLife Inc.
  • Hemarina SA
  • BioTime Inc.
  • Lifor SA
  • TissueGene Inc.
  • ToleroTech Inc


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Frequently Asked Questions

The Global Private Organ Preservation Market is 260 Mn as of 2023.

1.    Organ Preservation Market: Research Methodology
1.1. Research Data 
1.1.1.    Primary Data
1.1.2.    Secondary Data

1.2. Market Size Estimation
1.2.1.    Bottom-Up Approach
1.2.2.    Top-Down Approach

1.3. Market Breakdown and Data Triangulation
1.4. Assumptions

2.    Organ Preservation Market: Executive Summary
2.1. Market Overview
2.2. Market Size (2023) and Forecast (2024 – 2030) and Y-O-Y%
2.3. Market Size (USD) and Market Share (%) – By Segments and Regions

3.    Organ Preservation Market: Competitive Landscape
3.1. Stellar Competition Matrix
3.2. Key Players Benchmarking
3.2.1.    Company Name 
3.2.2.    Headquarter
3.2.3. Business Segment
3.2.4. End-user Segment
3.2.5. Y-O-Y%
3.2.6. Revenue (2023)
3.2.7. Profit Margin
3.2.8. Market Share
3.2.9. Company Locations

3.3. Market Structure
3.3.1.    Market Leaders 
3.3.2.    Market Followers
3.3.3.    Emerging Players

3.4. Consolidation of the Market
3.4.1. Strategic Initiatives 
3.4.2. Mergers and Acquisitions
3.4.3. Collaborations and Partnerships
3.4.4. Developments and Innovations

4.    Organ Preservation Market: Dynamics
4.1. Market Trends by Region
4.1.1. North America
4.1.2. Europe
4.1.3. Asia Pacific
4.1.4. Middle East and Africa
4.1.5. South America

4.2. Market Drivers 
4.3. Market Restraints
4.4. Market Opportunities
4.5. Market Challenges 
4.6. PORTER’s Five Forces Analysis
4.6.1. Intensity of the Rivalry
4.6.2. Threat of New Entrants
4.6.3. Bargaining Power of Suppliers
4.6.4. Bargaining Power of Buyers
4.6.5. Threat of Substitutes

4.7. PESTLE Analysis
4.7.1. Political Factors
4.7.2. Economic Factors
4.7.3. Social Factors
4.7.4. Technological Factors
4.7.5. Legal Factors
4.7.6. Environmental Factors

4.8. Technological Roadmap 
4.9. Regulatory Landscape
4.9.1.    Market Regulation by Region
4.9.1.1.    North America
4.9.1.2.    Europe
4.9.1.3.    Asia Pacific
4.9.1.4.    Middle East and Africa
4.9.1.5.    South America
4.9.2.    Impact of Regulations on Market Dynamics
4.9.3.    Government Schemes and Initiatives

5.    Organ Preservation Market Size and Forecast by Segments (by Value USD Million)
5.1. Organ Preservation Market Size and Forecast, By Type (2023-2030)
5.1.1.    Kidney
5.1.2.    Heart
5.1.3.    Lung
5.1.4.    Liver
5.1.5.    Pancreas

5.2. Organ Preservation Market Size and Forecast, By Technique (2023-2030)
5.2.1.    Static Cold Storage
5.2.2.    Hypothermic Machine Perfusion
5.2.3.    Normothermic Machine Perfusion

5.3. Organ Preservation Market Size and Forecast, By Application (2023-2030)
5.3.1.    Pharmaceuticals
5.3.2.    Organ Transplantation
5.3.3.    Speciality Centres
5.3.4.    Hospitals
5.3.5.    Others

5.4. Organ Preservation Market Size and Forecast, by Region (2023-2030)
5.4.1.    North America
5.4.2.    Europe
5.4.3.    Asia Pacific
5.4.4.    Middle East and Africa
5.4.5.    South America

6.    North America Organ Preservation Market Size and Forecast (by Value USD Million)
6.1. North America Organ Preservation Market Size and Forecast, By Type (2023-2030)
6.1.1.    Kidney
6.1.2.    Heart
6.1.3.    Lung
6.1.4.    Liver
6.1.5.    Pancreas

6.2. North America Organ Preservation Market Size and Forecast, By Technique (2023-2030)
6.2.1.    Static Cold Storage
6.2.2.    Hypothermic Machine Perfusion
6.2.3.    Normothermic Machine Perfusion

6.3. North America Organ Preservation Market Size and Forecast, By Application (2023-2030)
6.3.1.    Pharmaceuticals
6.3.2.    Organ Transplantation
6.3.3.    Speciality Centres
6.3.4.    Hospitals
6.3.5.    Others

6.4. North America Organ Preservation Market Size and Forecast, by Country (2023-2030)
6.4.1.    United States
6.4.2.    Canada
6.4.3.    Mexico

7.    Europe Organ Preservation Market Size and Forecast (by Value USD Million)
7.1. Europe Organ Preservation Market Size and Forecast, By Type (2023-2030)
7.2. Europe Organ Preservation Market Size and Forecast, By Technique (2023-2030)
7.3. Europe Organ Preservation Market Size and Forecast, By Application (2023-2030)
7.4. Europe Organ Preservation Market Size and Forecast, by Country (2023-2030)
7.4.1.    UK
7.4.2.    France
7.4.3.    Germany
7.4.4.    Italy
7.4.5.    Spain
7.4.6.    Sweden
7.4.7.    Austria
7.4.8.    Rest of Europe

8.    Asia Pacific Organ Preservation Market Size and Forecast (by Value USD Million)
8.1. Asia Pacific Organ Preservation Market Size and Forecast, By Type (2023-2030)
8.2. Asia Pacific Organ Preservation Market Size and Forecast, By Technique (2023-2030)
8.3. Asia Pacific Organ Preservation Market Size and Forecast, By Application (2023-2030)
8.4. Asia Pacific Organ Preservation Market Size and Forecast, by Country (2023-2030)
8.4.1.    China
8.4.2.    S Korea
8.4.3.    Japan
8.4.4.    India
8.4.5.    Australia
8.4.6.    Indonesia 
8.4.7.    Malaysia
8.4.8.    Vietnam
8.4.9.    Taiwan
8.4.10.    Bangladesh 
8.4.11.    Pakistan
8.4.12.    Rest of Asia Pacific

9.    Middle East and Africa Organ Preservation Market Size and Forecast (by Value USD Million)
9.1. Middle East and Africa Organ Preservation Market Size and Forecast, By Type (2023-2030)
9.2. Middle East and Africa Organ Preservation Market Size and Forecast, By Technique (2023-2030)
9.3. Middle East and Africa Organ Preservation Market Size and Forecast, By Application (2023-2030)
9.4. Middle East and Africa Organ Preservation Market Size and Forecast, by Country (2023-2030)
9.4.1.    South Africa
9.4.2.    GCC
9.4.3.    Egypt
9.4.4.    Nigeria
9.4.5.    Rest of ME&A

10.    South America Organ Preservation Market Size and Forecast (by Value USD Million)
10.1. South America Organ Preservation Market Size and Forecast, By Type (2023-2030)
10.2. South America Organ Preservation Market Size and Forecast, By Technique (2023-2030)
10.3. South America Organ Preservation Market Size and Forecast, By Application (2023-2030)
10.4. South America Organ Preservation Market Size and Forecast, by Country (2023-2030)
10.4.1.    Brazil
10.4.2.    Argentina
10.4.3.    Rest of South America

11.    Company Profile: Key players
11.1. 21st Century Medicine Inc.
11.1.1.     Company Overview
11.1.2.    Business Portfolio
11.1.3.    Financial Overview
11.1.3.1.    Total Revenue 
11.1.3.2.    Segment Revenue 
11.1.3.3.    Regional Revenue 
11.1.4.    SWOT Analysis
11.1.5.    Strategic Analysis
11.1.6.    Recent Developments 

11.2. Dr. Franz Köhler Chemie GmbH
11.3. Essential Pharmaceuticals LLC
11.4. IGL GmbH
11.5. Lifeline Scientific Inc.
11.6. Organ Recovery Systems Inc.
11.7. Preservation Solutions Inc.
11.8. XVIVO Perfusion AB
11.9. Bridge to Life Ltd.
11.10. Paragonix Technologies Inc.
11.11. TransMedics Inc.
11.12. Waters Medical Systems LLC
11.13. BioLife Solutions Inc.
11.14. Bristol-Myers Squibb Company
11.15. CryoLife Inc.
11.16. Hemarina SA
11.17. BioTime Inc.
11.18. Lifor SA
11.19. TissueGene Inc.
11.20. ToleroTech Inc

12.    Key Findings

13.    Industry Recommendations
13.1. Strategic Recommendations
13.2. Future Outlook

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